PTSD course and predictors in a 15 year longitudinal cohort following suspected serious injury

Investigating long-term posttraumatic stress disorder (PTSD) course and its predictors may guide prevention and early intervention strategies following trauma exposure, potentially reducing the longlasting impact of trauma. N = 155 emergency-admitted adults with (suspected) serious injury were repeatedly assessed until one-year post-trauma and completed a 12–15 year follow-up including a clinical PTSD interview. Adverse one-year PTSD trajectories; more exposure to additional potentially traumatic events and recent life stressors; and early post-trauma predictors (younger age, greater perceived impact of prior potentially traumatic events, higher heart rate) were significantly associated with higher PTSD symptom severity 12–15 years post-trauma. This study showed high consistency between one-year PTSD and its early post-trauma predictors with long-term PTSD outcomes. Early post-trauma predictors had predictive value up to 12–15 years. This suggests that early risk identification of one-year PTSD and subsequent effective early interventions also hold long-term beneficial effects for PTSD outcome.

Reference: 
Jeanet F. Karchoud, Chris M. Hoeboer, Irina Karaban, Joanne Mouthaan, Marit Sijbrandij, Miranda Olff, Rens van de Schoot & Mirjam van Zuiden | 2025
In: npj Mental Health Research ; ISSN: 2731-4251 | 4 | 35
https://doi.org/10.1038/s44184-025-00153-7
Keywords: 
Adults, Exposure, Injuries, Life Experiences, Longitudinal Study, Posttraumatic Stress Disorder, Predictors, Psychotrauma, PTSD (en), Statistical Analysis, Stressors, Traumatic events
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